Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules (Iucr Monographs on Crystallography)
- ISBN-13: 9780199639533
- Publisher: Oxford University Press
- Release Date: Nov 01, 2013
- Edition: 1
- Pages: 368 pages
- Dimensions: 0.9 x 7.6 x 9.8 inches
The major factors promoting the increasingly active use of SAXS/SANS are modern high brilliance X-ray and neutron sources, novel data analysis methods, and automation of the experiment, data processing and interpretation.
In this book, following the presentation of the basics of scattering from isotropic macromolecular solutions, modern instrumentation, experimental practice and advanced analysis techniques are explained. Advantages of X-rays (rapid data collection, small sample volumes) and of neutrons (contrast variation by hydrogen/deuterium exchange) are specifically highlighted. Examples of applications of the technique to different macromolecular systems are considered with specific emphasis on the synergistic use of SAXS/SANS with other structural, biophysical and computational techniques.
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