Bryan Edward Kolb (born 1947) is a Canadian neuroscientist, neuropsychologist, researcher, author and educator. Kolb's research focuses on the organization and functions of the cerebral cortex.
In 1976, Kolb's PhD thesis established the utility of employing rats for study of the prefrontal cortex in medical research. opening up a new venue for non-primate animal research in the prefrontal cortex and accelerating the development of new treatments that help victims of disease and cerebral injury. He was the first to demonstrate how the regrowth of brain cells accompanies restoration of brain function and also the first to show, with Terry Robinson, that psychoactive drugs change neuronal structures and networks permanently and in a manner such that later neuroplasticity is altered.Kolb has contributed extensively to the literature of neuroplasticity during development and in response to experience, drugs, hormones and injury; including how these changes influence behavior. Kolb's 1980 textbook Fundamentals of Neuropsychology, co-authored with colleague Ian Whishaw, helped define the field of neuropsychology and as of 2015 is in its seventh edition. Kolb has published over 400 articles and chapters including co-authoring popular textbooks in neuropsychology and behavioral neuroscience. He is a professor of Neuroscience and holds a Board of Governors' Research Chair in Neuroscience at the University of Lethbridge. He is a primary investigator at the Canadian Centre for Behavioral Neuroscience which he was key in establishing. In 2016 Kolb was inducted as an Officer of the Order of Canada.